The first game played by Doncaster Rovers in the new stadium was on 1 January 2007 against Huddersfield Town, whom they beat 3–0.[12] The game also saw the first three red cards in the new stadium.[13] Doncaster Rovers' centre forwardMark McCammon was the first player ever to score on the new pitch.
Doncaster's first loss at the stadium came five days later at the hands of Bolton Wanderers when they defeated the Rovers 4–0 in the 3rd Round of the FA Cup.[14] On 14 January 2007, Doncaster Rovers Belles' first match in the main stadium resulted in a 5–2 defeat to Leeds United, before a crowd of 1,797.[15]Vicky Exley was the first Belle to score on the new pitch.[16] The stadium hosted the final of the 2012–13 FA Women's Cup.[17] The highest ever attendance at the Keepmoat stadium was 15,001 for the visit of Leeds United.[18] Rovers also achieved attendances of over 14,800 at the Keepmoat Stadium in games against Sheffield Wednesday and Newcastle United.
Since the EFL require all matches to be played on grass pitches, the stadium will be used for all of Harrogate Town's matches for the first month of the 2020–21 season whilst the club replace their synthetic pitch at Wetherby Road.[19]